Rare Medical News
5 Facts you should know about
Alagille syndrome
1
An inherited liver disorder that also affects the heart, eyes, bones, kidneys, vasculature and other organs.
2
Individuals with AGS may have characteristic facial features, including prominent forehead and pointed chin, deep-set eyes and a straight nose.
3
An estimated 15% of people diagnosed with Alagille syndrome are at risk of severe liver disease and liver failure that can be life-threatening.
4
A problem with the JAG1 gene - usually a mutation in, but sometimes a deletion - causes more than 90% of Alagille syndrome cases.
5
Itchiness is often a very challenging symptom in Alagille syndrome
some patients scratch so hard and so frequently that it causes red marks, bleeding, and scarring.
Rare Medical News