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5 Facts you should know about

Castleman disease

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1

A rare condition that affects the lymph nodes and related tissues.

2

Castleman disease (CD) describes a group of at least 4 disorders

that share a spectrum of characteristic histopathological features but have a wide range of etiologies, presentations, treatments, and outcomes.

3

The average age of diagnosis for UCD patients is typically younger (fourth decade)

than for MCD patients (sixth decade).

4

The diagnosis of all 4 subtypes of CD first requires an excised lymph node biopsy.

5

Data suggest that UCD is more likely a clonal neoplastic process,

and the most likely cell of origin is stromal, specifically the follicular dendritic cell.

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