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5 Facts you should know about

Centronuclear myopathy

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1

A group of genetic muscle disorders

Centronuclear myopathy (CNM) is an umbrella term for a group of rare genetic muscle disorders.

2

Muscle weakness and associated disabilities

The clinical manifestations of CNM are most notably muscle weakness and associated disabilities.

3

Symptoms present at birth, but may develop later in life

Symptoms are often present at birth in the severe forms, but may first develop later in life, although onset in adulthood is unusual.

4

CNMs derive their name based on the central location of the muscle fiber (muscle cell) nucleus

CNMs derive their name based on the central location of the muscle fiber (muscle cell) nucleus - cell nuclei are abnormally located in the center of muscle cells instead of their normal location at the periphery.

5

Centronuclear myopathies remain ambulatory throughout their adult life

While some patients with centronuclear myopathies remain ambulatory throughout their adult life, others may never crawl or walk and may require wheelchair use for mobility.

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