Rare Medical News

5 Facts you should know about

Chronic Granulomatous Disease (CGD)

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1

A rare, inherited immunodeficiency

that affects certain white blood cells that leads to the formation of granulomas in many organs.

2

It is usually inherited

in an autosomal recessive or X-linked recessive manner.

3

Most people with CGD

are diagnosed in childhood, usually, before age 5.

4

The most important MOA is the impact

on the superoxide radical due to defective phagocyte NADPH oxidase.

5

The only cure for the disease

is an allogeneic hematopoietic stem cell transplantation.

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