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5 Facts you should know about
Cryoglobulinemia
1
Occurs when an abnormal immune system makes the protein cryoglobulin
2
At temperatures less than 98.6 degrees Fahrenheit, cryoglobulins become solid or gel-like and can block blood vessels
3
Symptoms may include skin ulcers, purpura Raynaud's phenomenon), joint pain, and kidney problems
4
Kidney disease - primarily membranoproliferative glomerulonephritis – occurs in about 1 in 3 patients
5
Cryoglobulinemia is also associated with immune system cancers, such as multiple myeloma or non-Hodgkins lymphoma
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