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5 Facts you should know about

Cryoglobulinemia

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1

Occurs when an abnormal immune system makes the protein cryoglobulin

2

At temperatures less than 98.6 degrees Fahrenheit, cryoglobulins become solid or gel-like and can block blood vessels

3

Symptoms may include skin ulcers, purpura Raynaud's phenomenon), joint pain, and kidney problems

4

Kidney disease - primarily membranoproliferative glomerulonephritis – occurs in about 1 in 3 patients

5

Cryoglobulinemia is also associated with immune system cancers, such as multiple myeloma or non-Hodgkins lymphoma

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