Rare Medical News
5 Facts you should know about
Generalized pustular psoriasis
1
Key symptoms of GPP include sterile pustules, pain, scaling, erythema, dryness, itching, burning, joint pain, leukocytosis, headache, fever, and fatigue.
2
Generalized pustular psoriasis (GPP) is heterogenous and can be a relapsing disease with recurrent flares or a persistent disease with intermittent flares.
3
GPP is phenotypically, histopathologically, and genetically distinct from plaque psoriasis.
4
GPP is considered a neutrophilic disease, whereas plaque psoriasis is considered an autoimmune disease.
5
The IL-36 pathway plays a key role in the pathogenesis of GPP, leading to the characteristic signs and symptoms of the disease.
Rare Medical News