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5 Facts you should know about

Graft versus host disease

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1

Chronic graft versus host disease (GVHD) is a dangerous complication of allogeneic stem cell transplantation

2

Symptoms may include skin rash, mouth sores, dry eyes, liver inflammation, development of scar tissue in the skin and joints, and damage to the lungs

3

Mild forms of chronic GVHD are often manageable with local or low-dose systemic immunosuppression and do not affect long-term survival

4

More severe forms of chronic GVHD require intensive medical management and adversely affect survival

5

Prednisone is the standard first-line therapy for chronic GVHD

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