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5 Facts you should know about

Hemophagocytic lymphohistiocytosis (HLH)

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1

A life-threatening disease of severe hyperinflammation caused by uncontrolled proliferation of activated lymphocytes and macrophages

2

HLH clinically manifests with fever, enlargement of the liver and spleen, enlarged lymph nodes, yellow discoloration of the skin and eyes, and a rash

3

It is classified as one of the cytokine storm syndromes

 

4

Laboratory findings may include elevated triglyceride levels, low fibrinogen levels, transaminitis, and elevated ferritin levels

 

5

The onset of HLH occurs under the age of one year in approximately 70 percent of cases

Rare Medical News

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