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5 Facts you should know about

Hypopituitarism

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1

Hypopituitarism refers to

deficiency of one or more hormones produced by the anterior pituitary or released from the posterior pituitary.

2

Onset can be

acute or insidious, and the most common cause in adulthood is a pituitary adenoma, or treatment with pituitary surgery or radiotherapy.

3

Most commonly,

growth hormone (GH) is lost first, then gonadotropins, and finally thyroid-stimulating hormone (TSH) and adrenocorticotropic hormone (ACTH).

4

Pituitary dysfunction must be distinguished

from anorexia nervosa , chronic liver disease, myotonia dystrophica, polyglandular autoimmune disease.

5

Hypopituitarism is associated with

excess mortality, a key risk factor being cortisol deficiency due to adrenocorticotropic hormone (ACTH) deficiency.

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