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5 Facts you should know about

Kennedy’s disease



An inherited motor neuron disease

Kennedy's disease is an inherited motor neuron disease that affects males.


Between the ages of 20 and 40

Onset of the disease is usually between the ages of 20 and 40, although it has been diagnosed in men from their teens to their 70s.


Affects the lower motor neurons

The disease affects the lower motor neurons that are responsible for the movement of many muscles in the legs, arms, mouth, and throat.


Caused by a change in the AR gene

Kennedy disease is caused by a change (mutation) in the AR gene that encodes for a protein known as the androgen receptor on the X chromosome.


Named after William R. Kennedy

Kennedy disease is named after William R. Kennedy, MD, who described the condition is the 1960s.

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