Rare Medical News

5 Facts you should know about

Lymphocytic vasculitis

fivefacts-light.svg

1

In lymphocytic vasculitis,

lymphocytes cause damage to blood vessels in the skin.

2

Hives, red or purplish discolored patches,

a bump (nodule), or an open sore (ulcer) have all been described as symptoms of this condition.

3

On microscopic examination, that there are neutrophils

in and around the walls of cutaneous venules, accompanied by deposits of fibrin in vessel walls and by neutrophilic nuclear dust.

4

Lymphocytic vasculitis is thought to be caused by a number of different factors,

such as infection, trauma, drug reaction, or an underlying condition such as arthritis.

5

Treatment Goals For Cystinuria Include Both Decreasing Urinary Cystine Concentrations And Increasing Cystine Solubility

The goal of treatment in cystinuria is to prevent recurrence of stones by decreasing urinary cystine concentrations to below the solubility limit (generally < 250 mg/L) or increasing the solubility of cystine. According to AUA guidelines, the first approach to treatment of cystinuria is initiation of therapeutic lifestyle changes involving increased fluid intake and restriction of sodium and protein, as well as urinary alkalinization therapy (3). If initial therapy fails to reduce urinary cystine concentrations to less than 250 mg/L or stones recur despite therapy, cystine-binding thiol drugs are the next step in treatment (3). The failure rate of initial therapy (therapeutic lifestyle changes and urinary alkalinization) may be as high as 55% (4).

Rare Medical News