Rare Medical News

5 Facts you should know about

Menetrier disease

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1

The stomach is characterized by large, tortuous gastric folds

in the fundus and body, with the antrum generally spared, giving the mucosa a cobblestone or cerebriform appearance.

2

The disorder is associated with excessive secretion

of transforming growth factor alpha (TGF-α).

3

This leads to excessive mucus production,

causing protein loss from the stomach and low or absent levels of stomach acid.

4

Symptoms may include pain in the upper middle region of the stomach,

nausea, vomiting, and diarrhea.

5

The cause of Ménétrier disease is unknown,

but it has been associated with HCMV infection in children and H. pylori infections in adults.

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