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5 Facts you should know about

Neuronal ceroid lipofuscinosis 2

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1

Symptoms of the CLN2 generally develop between ages two and four years.

2

The initial features usually include recurrent seizures and ataxia.

3

The CLNs were originally classified broadly according to age at onset, with CLN2 as the late infantile-onset (LINCL) form.

4

Children with CLN2 disease commonly experience a complete loss of cognitive abilities, motor function, and vision within the first decade of life.

5

Developmental skills such as standing, walking, and talking may not be achieved or are gradually lost.

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