Rare Medical News

5 Facts you should know about

Pulmonary alveolar proteinosis (PAP) – 2

fivefacts-light.svg

1

The cardinal signs and symptoms of PAP include shortness of breath,  cough, low-grade fever, and weight loss

2

PAP is characterized by an abnormal accumulation of surfactant-derived lipoprotein compounds within the alveoli

3

The abnormal accumulation of lipoproteinaceous compounds in PAP is due to impaired surfactant regulation and clearance

4

Anti–GM-CSF antibodies are believed to play a role in PAP

5

Individuals with PAP are more vulnerable to lung infections, such as bacterial pneumonia, AND mycobacterial or fungal infections

Rare Medical News