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5 Facts you should know about

Pulmonary lymphangioleiomyomatosis (LAM)

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1

A rare cystic lung disease that mostly affects women in their mid-forties

2

LAM is most commonly detected when a woman develops a pneumothorax

3

Diffuse cystic changes associated with multifocal clusters of smooth muscle-like cells (LAM cells) replace normal lung parenchyma, leading to progressive loss of lung function

4

Reports of exacerbations of LAM with the use of exogenous estrogens and during pregnancy suggest an association between hormones and clinical deterioration

5

There are 2 forms of LAM - a sporadic form, which occurs for unknown reasons, and a form that occurs in people with the tuberous sclerosis complex

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