Rare Medical News

5 Facts you should know about

Scleroderma

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1

Scleroderma is an autoimmune disorder

that may involve changes in the skin, blood vessels, muscles, and internal organs.

2

In addition to the skin,

the most commonly affected organs are lung and kidney.

3

It is characterized by

increased synthesis of collagen (leading to the sclerosis), damage to small blood vessels, activation of T lymphocytes, and production of altered connective tissue.

4

Risk factors include

family history, certain genetic factors, and exposure to silica.

5

Women are more often affected than men – about 80% of cases.

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