Rare Medical News

5 Facts you should know about

Tuberous sclerosis complex



TSC causes a combination of symptoms including

seizures, intellectual disability, developmental delay, behavioral problems, skin abnormalities, lung disease, and kidney disease.


The physical manifestations of TSC

are due to the formation of hamartia, hamartomas (benign growths such as facial angiofibroma and subependymal nodules), and very rarely, cancerous hamartoblastomas.


Three types of brain tumors are associated with TSC:

giant cell astrocytomas, cortical tubers, and subependymal nodules.


About 90% of people with TSC

develop a range of neurodevelopmental, behavioral, psychiatric, and psychosocial difficulties.


Around 80% of children under two-years-old with TSC

have at least one cardiac rhabdomyoma, and about 90% of those will have several.

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