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Disease Profile

Meralgia paresthetica

Prevalence estimates on Rare Medical Network websites are calculated based on data available from numerous sources, including US and European government statistics, the NIH, Orphanet, and published epidemiologic studies. Rare disease population data is recognized to be highly variable, and based on a wide variety of source data and methodologies, so the prevalence data on this site should be assumed to be estimated and cannot be considered to be absolutely correct.



US Estimated


Europe Estimated

Age of onset





Autosomal dominant A pathogenic variant in only one gene copy in each cell is sufficient to cause an autosomal dominant disease.


Autosomal recessive Pathogenic variants in both copies of each gene of the chromosome are needed to cause an autosomal recessive disease and observe the mutant phenotype.


dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.


recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder.


Mitochondrial or multigenic Mitochondrial genetic disorders can be caused by changes (mutations) in either the mitochondrial DNA or nuclear DNA that lead to dysfunction of the mitochondria and inadequate production of energy.


Multigenic or multifactor Inheritance involving many factors, of which at least one is genetic but none is of overwhelming importance, as in the causation of a disease by multiple genetic and environmental factors.


Not applicable


Other names (AKA)

Bernhardt-Roth syndrome; Lateral femoral cutaneous nerve entrapment; Meralgia paraesthetica familial (type)


Nervous System Diseases


Meralgia paresthetica is a condition characterized by numbness, tingling, and a burning pain in the outer thigh. Symptoms may worsen after walking or standing.[1] The condition usually affects only one side of the body, but both sides may be affected in up to 20% of cases.[2] Meralgia paresthetica is caused by compression of the lateral femoral cutaneous nerve, a sensory nerve to the skin on the outer thigh. Compression may be associated with various causes such as wearing tight clothing or a heavy tool belt, diabetes, nerve injury during local or regional surgery, weight gain, pregnancy, seatbelt injury, or rarely, a mass pressing on the nerve.[2][3][4][5] Treatment is based on the symptoms and severity in each person. Treatment for mild symptoms may include removing the cause of nerve compression, which may involve weight loss or wearing loose clothing. More severe pain may require a nerve block to temporarily relieve symptoms. Neurogenic pain medications (such as carbamazepine or gabapentin) typically are not as helpful but rarely relieve symptoms. People with very severe pain which is not relieved by nerve block may need to have surgery to release the nerve.[1][2][4]


This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.

Medical Terms Other Names
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Percent of people who have these symptoms is not available through HPO
Abnormality of the nervous system
Neurologic abnormalities
Neurological abnormality

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Autosomal dominant inheritance

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These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.

Where to Start

In-Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Meralgia paresthetica. Click on the link to view a sample search on this topic.


  1. Meralgia Paresthetica Information Page. National Institute of Neurological Disorders and Stroke (NINDS). June 20, 2018; https://www.ninds.nih.gov/Disorders/All-Disorders/Meralgia-Paresthetica-Information-Page.
  2. Sekul EA. Meralgia Paresthetica. Medscape Reference. Jul 31, 2018; https://emedicine.medscape.com/article/1141848-overview.
  3. Cheatham SW, Kolber MJ, Salamh PA. Meralgia paresthetica: a review of the literature. Int J Sports Phys Ther. December 2013; 8(6):883-893.
  4. Burning Thigh Pain (Meralgia Paresthetica). American Academy of Orthopaedic Surgeons. June, 2017; https://orthoinfo.aaos.org/en/diseases--conditions/burning-thigh-pain-meralgia-paresthetica/.
  5. Anderson BC. Meralgia paresthetica (lateral femoral cutaneous nerve entrapment). UpToDate. Waltham, MA: UpToDate; May 02, 2018; https://www.uptodate.com/contents/meralgia-paresthetica-lateral-femoral-cutaneous-nerve-entrapment.