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Carney complex

Carney complex and its subsets LAMB syndrome and NAME syndrome are autosomal dominant conditions comprising myxomas of the heart and skin, hyperpigmentation of the skin, and endocrine overactivity

Prevalence

Unknown

US Estimated

Unknown

Europe Estimated

Age of Onset

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ICD-10

D44.8

Inheritance

Autosomal dominant

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Autosomal recessive

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Mitochondrial/Multigenic

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X-linked dominant

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X-linked recessive

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5 Facts you should know

FACT

1

Individuals with Carney complex are at increased risk of developing cardiac myxomas

FACT

2

Cardiac myxomas occur at a young age and may occur in any or all cardiac chambers

FACT

3

Affected individuals also usually have changes in skin pigmentation

FACT

4

Signs and symptoms of this condition commonly begin in the teens or early adulthood

FACT

5

Pale brown to black lentigines are the most common presenting feature of CNC and typically increase in number at puberty

Carney complex is also known as...

Carney complex

Carney syndrome; CNC1; Carney myxoma-endocrine complex; CAR; Myxoma, spotty pigmentation, and endocrine overactivity; NAME syndrome; LAMB syndrome; Myxoma - spotty pigmentation - endocrine overactivity; Myxoma-spotty pigmentation-endocrine overactivity syndrome

What’s your Rare IQ?

Which of the following is not a typical symptom of the Carney complex?

Common signs & symptoms

Pigmented micronodular adrenocortical disease

Multiple lentigines

Abnormal prolactin level

Abnormality of circulating adrenocorticotropin level

Blue nevus

Cardiac myxoma

Enlarged polycystic ovaries

Enlarged ovaries with cysts

Hirsutism

Excessive hairiness

Top Clinical Trials

At the time this analysis was conducted, there were no interventional clinical studies being conducted.

Top Treatments in Research

At the time this analysis was conducted, there were no treatments in development for this disease.